aggrecanase相关论文
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Objective: This study was performed to evaluate the role of CXCL12/CXCR4 axis in aggrecanase-mediated cartilage breakdow......
,Effects of RNAi-mediated inhibition of aggrecanase-1 and aggrecanase-2 on rat costochondral chondro
Aim:Failure of transplanted cartilage or allogenic chondrocytes is attributed mainly to immunological rejection and cart......
Promotion of the articular cartilage proteoglycan degradation by T-2 toxin and selenium protective e
Objective: To identify the relationship between T-2 toxin and Kashin-Beck disease (KBD), the effects of T-2 toxin on agg......
目的：探讨ADAMTS-4、ADAMTS-5在膝骨关节炎不同时期关节液中的表达。方法：收治膝骨关节炎患者124例，包括早期膝骨关节炎45例、中期膝......
目的探讨α2巨球蛋白对聚集素酶ADAMTS-4和5表达以及聚集素分解的影响。方法利用ADAMTS-4／-5和不同浓度的α2巨球蛋白（0、10、20、30......
目的：探讨塞来昔布对中晚期骨关节炎（OA）患者关节软骨中聚蛋白多糖酶1（aggre-canase-1,Agase-1或ADAMTS-4）及基质金属蛋白酶组织抑制因......
目的在细胞水平,探讨1α,25（OH）2D3对受到多种促炎症因子干预的大鼠关节软骨细胞蛋白聚糖合成和分解的调节作用。方法分别使用促炎症......
骨关节炎（osteoarthritis,OA）是一种以关节软骨退行性变和新骨形成为特征的非炎症性疾病,是关节炎最常见的类型。本文回顾了与软骨代......
骨性关节炎（osteoarthrits OA）是以关节软骨缺损为特点的一种退行性的骨关节疾病,其病因目前尚不十分清楚,但多种蛋白水解酶活性增高......
目的：探讨臭氧对中晚期骨关节炎（osteoarthritis,OA）患者关节软骨中聚蛋白多糖酶1（aggrecanase-1,Agase-1 or ADAMTS-4）及基质金属蛋白......
